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Reliability and Validity of the Korean Version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire to Assess Chemotherapy-induced Peripheral Neuropathy

Journal of Korean Academy of Nursing 2014³â 44±Ç 6È£ p.735 ~ 742
KMID : 0806120140440060735
±èÇý¿µ ( Kim Hye-Young ) - Chonbuk National University College of Nursing

°­Á¤Èñ ( Kang Jeong-Hee ) - Chonbuk National University College of Nursing
À±ÇöÁ¶ ( Youn Hyun-Jo ) - Chonbuk National University Medical School Department of Surgery
¼ÒÇâ¼÷ ( So Hyang-Sook ) - Chonnam National University College of Nursing
¼ÛÁöÀº ( Song Chi-Eun ) - Chonnam National University Hwasun Hospital Department of Oncology
Á¤¼ºÈÄ ( Jung Sung-Hoo ) - Chonbuk National University Medical School Department of Surgery
±è¼º·Ä ( Kim Sung-Reul ) - Chonbuk National University College of Nursing
±èÁö¿µ ( Kim Ji-Young ) - Chonbuk National University College of Nursing

Abstract

Purpose: This study was performed to assess the reliability and validity of the Korean version of European Organization for Research andTreatment of Cancer Quality of Life Questionnaire - Chemotherapy-induced peripheral neuropathy 20 items (EORTC QLQ-CIPN20) in patientsreceiving neurotoxic chemotherapy.

Methods: A convenience sample of 249 Korean cancer patients, previously or currently, beingtreated with peripheral neurotoxic chemotherapeutic agents were asked to fill in the questionnaire. Collected data were analyzed usingSPSS 21.0 and AMOS 21.0. Construct validity, known-group validity, concurrent validity, and internal consistency reliability of the Koreanversion of the QLQ-CIPN20 were evaluated.

Results: Factor analysis confirmed 3 dimensions of CIPN: sensory, motor, and autonomic. The factor loadings of the 20 items on the 3 subscales ranged from .38 to .85. The 3 subscale-model was validated by confirmatory factoranalysis (GFI=.90, AGFI=.86, RMSR=.05, NFI=.87, and CFI=.94), and concurrent validity was demonstrated with the EORTC QLQC30. Furthermore, the QLQ-CIPN20 established known-group validity. The Cronbach¡¯s alpha coefficients for internal consistency of thesubscales ranged from .73 to .89.

Conclusion: The Korean version of the EORTC QLQ-CIPN20 showed satisfactory construct, concurrent,and known-group validity, as well as internal reliability.
KeyWords

Validity, Reliability, Chemotherapy, Peripheral neuropathies
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